A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
NCT07140913
This study is recruiting at 20 US sites in 8 states, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to evaluate the efficacy and safety of adjunctive KarXT for the treatment of mania in participants with Bipolar-I Disorder.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Mania
- Bipolar Disorder
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Bristol-Myers Squibb
- Last updated on ClinicalTrials.gov
- June 23, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arkansas · 2
- Pillar Clinical Research - Bentonville · Bentonville, AR
- Pillar Clinical Research- Little Rock · Little Rock, AR
California · 7
- Clinical Innovations, Inc. dba CITrials · Bellflower, CA
- Inland Psychiatric Medical Group. · Chino, CA
- Proscience Research Group · Culver City, CA
- Omega Clinical Trials - La Habra · La Habra, CA
- Catalina Research Institute, LLC · Montclair, CA
- NRC Research Institute · Orange, CA
- Clinical Innovations, Inc. dba CITrials · Riverside, CA
Florida · 3
- Velocity Clinical Research, Hallandale Beach · Hallandale, FL
- South Florida Research Phase I-IV · Miami, FL
- Health Synergy Clinical Research · West Palm Beach, FL
Georgia · 1
- CenExel iResearch, LLC · Savannah, GA
Illinois · 1
- Pillar Clinical Research -Chicago · Chicago, IL
Missouri · 1
- Arch Clinical Trials · St Louis, MO
New York · 1
- Richmond Behavioral Associates · Staten Island, NY
Texas · 4
- Community Clinical Research · Austin, TX
- Elevate Clinical Research-Houston · Houston, TX
- Prime Clinical Research - Mansfield · Mansfield, TX
- Pillar Clinical Research - Richardson · Richardson, TX
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.