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COMPASS Study for Metastatic Castration-resistant Prostate Cancer

NCT07050433

This study is recruiting at 4 US sites in 4 states, according to its ClinicalTrials.gov record last updated .

Summary

This study is a companion to the SYNERGY-201 clinical trial (NCT06228053), which investigates SX-682 and enzalutamide in individuals with prostate cancer. Individuals must be participating in SYNERGY-201 in order to participate in this study. The purpose of this companion study is to learn more about biomarkers, particularly a biomarker called CXCR2, and investigate if CXCR2 can predict who will receive benefit from the SYNERGY-201 drug combination. This study will also investigate how CXCR2 and other biomarkers change over time when participants receive the SYNERGY-201 drug combination.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Prostate Cancer

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 years and older
Sex
Male
Healthy volunteers
Not accepted
Sponsor
Duke University
Last updated on ClinicalTrials.gov
August 27, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • UCSF Helen Diller Family Comprehensive Cancer Center · San Francisco, CA

Michigan · 1

  • Rogel Cancer Center · Ann Arbor, MI

North Carolina · 1

  • Duke University · Durham, NC

Wisconsin · 1

  • University of Wisconsin Carbone Cancer Center · Madison, WI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.