BoxX-NoAF Clinical Trial

Summary

Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial to evaluate if prophylactic ablation and exclusion of the Left Atrial Appendage at the time of other routine cardiac surgery can reduce the incidence of post operative AF and clinical AF during long term follow up in patients who have not yet developed AF but are at risk.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Post Operative Atrial Fibrillation
• Atrial Fibrillation, Postoperative

Eligibility basics and study details

Study type

Interventional

Phase

Not applicable

Ages

65 years and older

Sex

All

Healthy volunteers

Accepted

Sponsor

AtriCure, Inc.

Last updated on ClinicalTrials.gov

October 7, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites