Role of Transposable Elements in Septic Immune Aging

Summary

The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: Do transposable elements prematurely age the immune systems of patients with sepsis? Do transposable elements correlate with increased mortality in patients with sepsis in the ICU? Do transposable elements correlate with increased amount of secondary infections in patients with sepsis in the ICU? Participants will have blood drawn from them but will not be subjected to additional interventions.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Sepsis
• Sepsis and Septic Shock
• Sepsis With Multiple Organ Dysfunction (MOD)
• Sepsis With Acute Organ Dysfunction
• Sepsis, Severe
• Sepsis at Intensive Care Unit
• Sepsis, Severe Sepsis and Septic Shock
• Sepsis, Septic Shock

Eligibility basics and study details

Study type

Observational

Phase

Not applicable

Ages

18 years and older

Sex

All

Healthy volunteers

Accepted

Sponsor

University of California, San Francisco

Last updated on ClinicalTrials.gov

January 30, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites