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Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI

NCT06763172

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This research study aims to determine whether and how caffeine intake affects learning process through reward feedback compared to placebo. The data acquired from this study would improve our understanding on the consequence and mechanism of caffeine intake in the aspect of learning process. Participants will perform a reinforcement learning task (i.e. Probabilistic Selection Task) and a motor inhibition task (i.e. Go/NoGo task) in a brain scan. The scan will be done with the Siemens Biograph mMR positron emission tomography (PET)/ magnetic resonance imaging (MRI) 3 Tesla scanner.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Healthy
  • Caffeine
  • Adenosine
  • Dopamine D2/3 Receptor Availability

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 to 45 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Hsiao-Ying Wey
Last updated on ClinicalTrials.gov
January 9, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Massachusetts · 1

  • Athinoula A. Martinos Center for Biomedical Imaging · Charlestown, MA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.