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MAINTAIN (Mucosal AblatIoN Therapy After INcretins)

NCT06734312

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to assess the effect of gastric fundal mucosal ablation (GFMA) on weight trajectory following discontinuation of once-weekly semaglutide or tirzepatide in adults with obesity. In this study, GFMA will be performed on patients who have experienced > 10% weight loss with GLP-1 therapy and who plan to discontinue use of GLP-1 medications for the duration of the study.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obesity and Obesity-related Medical Conditions
  • Obesity and Overweight
  • Obesity Prevention
  • Obesity Recidivism
  • GLP-1
  • Ablation Techniques

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
21 to 65 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Dr. Christopher McGowan
Last updated on ClinicalTrials.gov
March 21, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

North Carolina · 1

  • True You Weight Loss · Cary, NC

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.