Neonatal Platelet Transfusion Threshold Trial
NCT06676904
This study is recruiting at 20 US sites in 15 states, according to its ClinicalTrials.gov record last updated .
Summary
The objective of the NeoPlaTT trial is to test whether, among extremely preterm infants born at 23 0/7 to 26 6/7 weeks' gestation, a lower platelet transfusion threshold, compared to a higher threshold, improves survival without major or severe bleeding up to 40 0/7 weeks' postmenstrual age (PMA).
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Thrombocytopenia
- Neonatal
- Platelet Transfusion
- Infant, Newborn, Diseases
- Infant, Extremely Low Birth Weight
- Infant, Small for Gestational Age
- Thrombosis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 1 Hour to 48 Hours
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- NICHD Neonatal Research Network
- Last updated on ClinicalTrials.gov
- March 25, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Alabama · 1
- University of Alabama at Birmingham · Birmingham, AL
California · 2
- Stanford University · Palo Alto, CA
- Sharp Mary Birch Hospital for Women & Newborns · San Diego, CA
Colorado · 1
- University of Colorado · Aurora, CO
Georgia · 1
- Emory University · Atlanta, GA
Illinois · 1
- Northwestern Lurie Children's Hospital of Chicago · Chicago, IL
Iowa · 1
- University of Iowa · Iowa City, IA
Massachusetts · 1
- Beth Israel Deaconess Medical Center · Boston, MA
New Mexico · 1
- University of New Mexico · Albuquerque, NM
New York · 1
- University of Rochester · Rochester, NY
North Carolina · 1
- Duke University · Durham, NC
Ohio · 3
- Cincinnati Children's Medical Center · Cincinnati, OH
- Case Western Reserve University, Rainbow Babies and Children's Hospital · Cleveland, OH
- Nationwide Children's Hospital · Columbus, OH
Pennsylvania · 1
- University of Pennsylvania · Philadelphia, PA
Tennessee · 1
- Vanderbilt University · Nashville, TN
Texas · 3
- University of Texas Southwestern Medical Center at Dallas · Dallas, TX
- University of Texas Health Science Center at Houston · Houston, TX
- Pediatrix Medical Group · San Antonio, TX
Utah · 1
- University of Utah · Salt Lake City, UT
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.