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Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

NCT06665646

This study is recruiting at 4 US sites in 4 states, according to its ClinicalTrials.gov record last updated .

Summary

The clinical schedule will consist of 3 injections of CD40.HIVRI.Env (VRIPRO) at weeks 0, 4, and 24.40 volunteers without HIV and in overall good health, aged 18 to 60 years, who previously participated in the HVTN 706 trial.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • HIV Infections

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 to 60 years
Sex
All
Healthy volunteers
Accepted
Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Last updated on ClinicalTrials.gov
September 18, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 1

  • Bridge HIV CRS · San Francisco, CA

Massachusetts · 1

  • Brigham and Women's Hospital Vaccine CRS (BWH VCRS) · Boston, MA

Pennsylvania · 1

  • Penn Prevention CRS (Site ID# 30310) · Philadelphia, PA

Tennessee · 1

  • Vanderbilt Vaccine (VV) CRS · Nashville, TN

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.