A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
NCT06629779
This study is recruiting at 39 US sites in 9 states, according to its ClinicalTrials.gov record last updated .
Summary
This study will explore whether a combination of the investigational drug PF-06821497 and enzalutamide will work better than taking enzalutamide alone in participants with mCRPC who are ARSi or abiraterone naïve.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Metastatic Castration-Resistant Prostate Cancer
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 3
- Ages
- 18 years and older
- Sex
- Male
- Healthy volunteers
- Not accepted
- Sponsor
- Pfizer
- Last updated on ClinicalTrials.gov
- October 14, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Arizona · 9
- Ironwood Cancer & Research Centers · Chandler, AZ
- Ironwood Cancer & Research Centers · Gilbert, AZ
- Ironwood Cancer & Research Centers · Glendale, AZ
- Palo Verde Hematology Oncology · Glendale, AZ
- Ironwood Cancer & Research Centers · Goodyear, AZ
- Ironwood Cancer & Research Centers · Mesa, AZ
- Ironwood Cancer & Research Centers · Mesa, AZ
- Ironwood Cancer & Research Centers · Phoenix, AZ
- Ironwood Cancer & Research Centers · Scottsdale, AZ
Arkansas · 4
- Highlands Oncology · Fayetteville, AR
- Arkansas Urology - Little Rock · Little Rock, AR
- Highlands Oncology · Rogers, AR
- Highlands Oncology Group · Springdale, AR
California · 8
- Los Angeles Cancer Network (LACN) · Anaheim, CA
- Los Angeles Cancer Network (LACN) · Fountain Valley, CA
- Los Angeles Cancer Network (LACN) · Glendale, CA
- Los Angeles Cancer Network (LACN) · Glendale, CA
- Los Angeles Cancer Network (LACN) · Laguna Hills, CA
- Los Angeles Cancer Network (LACN) · Los Angeles, CA
- Los Angeles Cancer Network (LACN) · Los Angeles, CA
- Medical Oncology Associates of San Diego · San Diego, CA
Illinois · 2
- Blessing Hospital · Quincy, IL
- Blessing Physician Services · Quincy, IL
New Mexico · 1
- CHRISTUS St. Vincent Regional Cancer Center · Santa Fe, NM
New York · 2
- Montefiore Medical Center · The Bronx, NY
- Montefiore Medical Center - Medical Park · The Bronx, NY
South Carolina · 4
- AUC Urologists, LLC · Myrtle Beach, SC
- Carolina Urologic Research Center, LLC · Myrtle Beach, SC
- Grand Strand Medical Center · Myrtle Beach, SC
- Parkway Surgery Center · Myrtle Beach, SC
Texas · 1
- USA Clinical Trials · San Antonio, TX
Washington · 8
- Northwest Medical Specialties, PLLC · Bonney Lake, WA
- Northwest Medical Specialties, PLLC · Federal Way, WA
- Northwest Medical Specialties, PLLC · Gig Harbor, WA
- Northwest Medical Specialties, PLLC · Puyallup, WA
- Fred Hutchinson Cancer Center · Seattle, WA
- Harborview Medical Center · Seattle, WA
- University of Washington Medical Center - Montlake · Seattle, WA
- Northwest Medical Specialties, PLLC · Tacoma, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.