Mechanical Alignment vs Kalipered Kinematic Alignment Total Knee Arthroplasty

Summary

Knee replacement surgery can be performed in one of two ways. Traditionally the goal was for the new joint to be in a neutral position with respect to the femur (thigh bone). This is called Mechanical Alignment (MA). The neutral position is different than the human knee's natural position, so MA often requires the surgeon to make additional cuts to the ligaments and other soft tissue around the knee. More recently surgeons have started to place the new joint in a position that more closely replicates the natural alignment of the human knee. This is called Kinemetic Alignment (KA).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Knee Osteoarthritis
• Knee Arthropathy

Eligibility basics and study details

Study type

Interventional

Phase

Not applicable

Ages

21 to 79 years

Sex

All

Healthy volunteers

Not accepted

Sponsor

Northwestern University

Last updated on ClinicalTrials.gov

March 24, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

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