ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL
NCT06146842
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
The primary objective of our study is to use a biased coin up-down allocation methodology to estimate the dose of bupivacaine required after the lidocaine test dose to achieve initial effective comfort in 90% of patients (post test-dose ED90) via the epidural (DPE or EPL) technique in women undergoing labor induction or augmentation; the investigators hypothesize that the investigators will be able to determine the post test-dose ED90 of bupivacaine for each technique with adequate precision to inform the optimal doses to study in a subsequent randomized trial comparing the analgesic effects…
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Labor Pain
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 4
- Ages
- Any age
- Sex
- Female
- Healthy volunteers
- Accepted
- Sponsor
- Brigham and Women's Hospital
- Last updated on ClinicalTrials.gov
- July 13, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Massachusetts · 1
- Brigham and Women's Hospital · Boston, MA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.