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ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

NCT06141993

This study is recruiting at 3 US sites in 3 states, according to its ClinicalTrials.gov record last updated .

Summary

This study will follow men with metastatic castration resistant prostate cancer throughout their standard of care treatment for their disease to determine if the presence of different genes or proteins can predict which patients respond to the cancer treatment they receive. As tumors grow and begin to spread, they may release cells into patients' bloodstream. These cells are called "circulating tumor cells", or CTCs. CTCs can be used to look for differences in "biomarkers" (genes or proteins that may change based on how a person is or is not responding to treatment).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Prostate Cancer
  • Prostate Adenocarcinoma
  • Prostate Cancer Metastatic
  • Castration-resistant Prostate Cancer

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 years and older
Sex
Male
Healthy volunteers
Not accepted
Sponsor
Duke University
Last updated on ClinicalTrials.gov
October 15, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

New York · 1

  • Memorial Sloan Kettering Cancer Center · New York, NY

North Carolina · 1

  • Duke University Medical Center · Durham, NC

Wisconsin · 1

  • University of Wisconsin-Madison · Madison, WI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.