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Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

NCT05991453

This study is recruiting at 22 US sites in 16 states, according to its ClinicalTrials.gov record last updated .

Summary

The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Surgery-Complications
  • Anesthesia Complication
  • Anesthesia Awareness
  • Anesthesia
  • Surgery
  • Quality of Life
  • Pain, Postoperative
  • Anesthesia Morbidity

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Washington University School of Medicine
Last updated on ClinicalTrials.gov
September 4, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arkansas · 1

  • University of Arkansas for Medical Sciences (UAMS) · Little Rock, AR

California · 1

  • University of California San Francisco · San Francisco, CA

Connecticut · 1

  • Yale School of Medicine · New Haven, CT

Maryland · 1

  • Johns Hopkins School of Medicine · Baltimore, MD

Massachusetts · 2

  • Brigham & Women's · Boston, MA
  • Massachusetts General Hospital · Boston, MA

Michigan · 2

  • University of Michigan · Ann Arbor, MI
  • Henry Ford Health · Detroit, MI

Missouri · 1

  • Washington University School of Medicine · St Louis, MO

New Hampshire · 1

  • Dartmouth Hitchcock Medical Center · Lebanon, NH

New York · 2

  • NYU Langone · New York, NY
  • Weill Cornell Medicine · New York, NY

North Carolina · 3

  • University of North Carolina School of Medicine · Chapel Hill, NC
  • Duke University · Durham, NC
  • Wake Forest · Winston-Salem, NC

Oregon · 1

  • Oregon Health and Sciences University · Portland, OR

Pennsylvania · 1

  • Temple University · Philadelphia, PA

Texas · 2

  • University of Texas Southwestern · Dallas, TX
  • University of Texas - MD Anderson · Houston, TX

Utah · 1

  • University of Utah - Medical · Salt Lake City, UT

Virginia · 1

  • UVA Health · Charlottesville, VA

Washington · 1

  • University of Washington · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.