The Osteoarthritis Prevention Study
NCT05946044
This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .
Summary
The goal of this study is to establish the efficacy of an intervention of dietary weight loss, exercise, and weight-loss maintenance for knee Osteoarthritis (OA) prevention in adult females aged ≥ 50 years with obesity and no or infrequent knee pain. The primary aim is to compare the effects of a dietary weight loss, exercise, and weight-loss maintenance to an attention control group in preventing the development of structural Magnetic Resonance Imaging (MRI) knee OA.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Osteoarthritis, Knee
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 50 years and older
- Sex
- Female
- Healthy volunteers
- Accepted
- Sponsor
- Wake Forest University
- Last updated on ClinicalTrials.gov
- July 23, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Massachusetts · 1
- Brigham and Women's Hospital · Boston, MA
North Carolina · 1
- Wake Forest University · Winston-Salem, NC
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.