Variations in Ketone Metabolism
NCT05924295
This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .
Summary
This outcome of this study will elucidate how the phenotype of the individual modulates the KE metabolic effect. Most studies of KE have been in homogenous populations, usually young, male athletes. However, two striking experiments using identical, body weight adjusted KE doses in healthy and obese individuals found that BHB area under the curve (AUC) and removal was reduced by obesity and poor metabolic health. Similarly, ketone infusion experiments found that diabetes, obesity, and insulin resistance alter BHB metabolism. It is important to determine how obesity affects KE 'sensitivity' (i.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Ketosis
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Not applicable
- Ages
- 20 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Ohio State University
- Last updated on ClinicalTrials.gov
- May 14, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
California · 1
- The Buck Institute · Novato, CA
Ohio · 1
- The Ohio State University · Columbus, OH
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.