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Metabolic Adaptations to Weight Loss With and Without Exercise

NCT05806801

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Study Purpose: The combination of caloric restriction and exercise is the most common first-line treatment for obesity-related disorders, yet we know very little about how these two very different treatments work together. A deeper understanding about mechanisms underlying the health benefits of adding exercise to a weight loss program will not only aid efforts to optimize more effective lifestyle interventions, but it can also uncover novel targets for the treatment/prevention of obesity-related diseases.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Obesity
  • Metabolic Disease
  • Metabolic Syndrome
  • Insulin Sensitivity
  • Insulin Resistance
  • Weight Loss

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
18 to 40 years
Sex
All
Healthy volunteers
Accepted
Sponsor
University of Michigan
Last updated on ClinicalTrials.gov
April 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Michigan · 1

  • University of Michigan · Ann Arbor, MI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.