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Exogenous and Endogenous Risk Factors for Early-onset Colorectal Cancer

NCT05732623

This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .

Summary

An increase in early-onset colorectal cancers (eoCRC), defined as a CRC before 50 years, is confirmed globally. CRC pathogenesis has been associated with several risk factors (family history, germline pathogenic variants, obesity, alcohol, physical activity, red meat, and a Western diet). Design: an international, multicenter, retrospective case-control study of prospectively enrolled patients; low-risk intervention study as it will perform a fecal occult blood test Endpoint: predictive power of a semi-quantitative food frequency questionnaire (SQFFQ) developed for eoCRC.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Colorectal Cancer
  • Early Onset Colorectal Cancer
  • Diet Habit
  • Risk Reduction

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 to 49 years
Sex
All
Healthy volunteers
Accepted
Sponsor
San Raffaele University
Last updated on ClinicalTrials.gov
April 24, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Colorado · 1

  • Department of Medicine-Gastroenterology, Denver Veterans Affairs Medical Center, University of Colorado Hospital · Denver, CO

Illinois · 1

  • Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine University of Chicago Medicine · Chicago, IL

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.