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Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

NCT05658731

This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this trial is to determine whether it is possible to minimize radiation dose to parts of the brain that are important for thinking and learning in children who require radiation to treat their tumor, and if this will help reduce neurocognitive (thinking and learning) impairments in these patients. Patients with newly diagnosed brain or head and neck tumors who are having radiation therapy will have neurocognitive testing and MRI imaging (both research and for regular care) done as part of their participation in the study.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Brain Tumor
  • Head and Neck Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
1 year to 26 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Last updated on ClinicalTrials.gov
June 29, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

District of Columbia · 1

  • Sibley Memorial Hospital · Washington D.C., DC

Maryland · 1

  • Johns Hopkins Hospital · Baltimore, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.