Trial of a Harm Reduction Strategy for People With HIV Who Smoke Cigarettes

Summary

Cigarette smoking is now the leading killer of people with HIV (PWH) in the US, and most cessation strategies tried to date have failed to increase long-term quit rates. An "all or none" approach to smoking cessation in PWH offers little benefit to the large majority of PWH who are unable or unwilling to quit. In this proposal we argue that a harm reduction approach (i.e., cut down, get screened for lung cancer, control your blood pressure and cholesterol) has the potential to yield significant benefits in terms of the private and public health of PWH in the US.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Hiv
• Tobacco Use

Eligibility basics and study details

Study type

Interventional

Phase

Not applicable

Ages

40 to 79 years

Sex

All

Healthy volunteers

Accepted

Sponsor

Montefiore Medical Center

Last updated on ClinicalTrials.gov

April 21, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites