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Focused Extracorporeal Shockwave Therapy for Knee Arthritis

NCT05596591

This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Subchondral bone marrow lesions (BMLs) in knee osteoarthritis (OA) are strongly associated with presence and severity of knee pain, structural deterioration, disease progression with an increased risk of total knee arthroplasty. OA-related BMLs may regress or resolve within 30 months which could be associated with long lasting disability. It has been reported that BMLs persist in the majority of knee OA patients. Different treatment strategies have been proposed including rest and protected weight-bearing, bisphosphonates, subchondroplasty and intraosseous orthobiologic injection.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Bone Marrow Edema
  • Knee Osteoarthritis
  • Knee Pain Chronic

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
30 to 80 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Kessler Foundation
Last updated on ClinicalTrials.gov
March 27, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

New Jersey · 2

  • New Jersey Regenerative Institute · Cedar Knolls, NJ
  • Nathan Hogaboom · West Orange, NJ

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.