Sleep Disordered Breathing With Opioid Use
NCT05589753
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
There is an increased risk for sleep disordered breathing (SDB), sleep-related hypoventilation and irregular breathing in individuals on chronic prescription opioid medications. Almost 30% of a veteran sleep clinic population had opioid-associated central sleep apnea (CSA). The proposal aims to identity whether oxygen and acetazolamide can be effective in reducing unstable breathing and eliminating sleep apnea in chronic opioid use via different mechanisms. We will study additional clinical parameters like quality of life, sleep and pain in patients with and without opioid use.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Sleep Apnea
- Opioid Use
- Sleep Disordered Breathing
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1/2
- Ages
- 18 to 89 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- VA Office of Research and Development
- Last updated on ClinicalTrials.gov
- July 1, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Michigan · 1
- John D. Dingell VA Medical Center, Detroit, MI · Detroit, MI
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.