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Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases

NCT05357612

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

It is hypothesize that patients with clinically diagnosed neurodegenerative diseases will have significantly different receptor occupancy of 5HT2A receptors compared to a healthy age/sex-matched control group. This will be tested by measuring 5HT2A receptor density using the PET radioligand (R)-[18F]MH.MZ in both populations.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Neurodegenerative Diseases
  • Parkinson Disease
  • Parkinson Disease Psychosis

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
50 to 85 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Vanderbilt University Medical Center
Last updated on ClinicalTrials.gov
August 7, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Tennessee · 1

  • Vanderbilt University Medical Center · Nashville, TN

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.