Usage of Spirometry in Managing IgG Therapy in CVID With Airway Disease

Summary

Although there is evidence in the literature that gammaglobulin replacement therapy can lead to a reduction in the prevalence of pulmonary infection and improved lung function, there is no published study to guide immunologists regarding the use of spirometry in titrating IG therapy to assist in the management of immunodeficiency patients with regards to gammaglobulin replacement therapy. The investigators propose to study the use of spirometry to identify patients that could potentially benefit from an increase in IGRT.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Common Variable Immunodeficiency

Eligibility basics and study details

Study type

Interventional

Phase

Phase 4

Ages

21 years and older

Sex

All

Healthy volunteers

Accepted

Sponsor

University of Alabama at Birmingham

Last updated on ClinicalTrials.gov

May 4, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites