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Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers

NCT05121051

This study is recruiting at 3 US sites in 3 states, according to its ClinicalTrials.gov record last updated .

Summary

This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers. Broccoli seed and sprout extract may help break down and remove toxic substances caused by tobacco use and possibly produce substances that may protect cells from tobacco smoke-induced damage in current smokers.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Cigarette Smoking-Related Carcinoma

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
National Cancer Institute (NCI)
Last updated on ClinicalTrials.gov
July 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Arizona · 1

  • University of Arizona Cancer Center - Prevention Research Clinic · Tucson, AZ

District of Columbia · 1

  • George Washington University Medical Center · Washington D.C., DC

New York · 1

  • Roswell Park Cancer Institute · Buffalo, NY

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.