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SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

NCT05057806

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The study team will examine the effects of SGLT2i (and SGLT2i-induced increases in plasma ketone concentrations) on skeletal muscle and cardiac ketone uptake, skeletal muscle bioenergetics, cardiopulmonary exercise capacity, and patient-reported functional outcomes.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Type2 Diabetes
  • Heart Failure With Preserved Ejection Fraction

Eligibility basics and study details

Study type
Interventional
Phase
Early Phase 1
Ages
18 to 80 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
The University of Texas Health Science Center at San Antonio
Last updated on ClinicalTrials.gov
April 6, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Texas · 1

  • University of Texas Health Science Center at San Antonio · San Antonio, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.