Cardiovascular Manifestations of MR Activation in Primary Aldosteronism: Pilot Clinical Study

Summary

This research study aims to learn more about the impact the hormone aldosterone on the heart. Primary aldosteronism is a condition where the body's adrenal glands make too much of the hormone aldosterone, which can cause high blood pressure and increase the risk of heart and kidney disease. Treatment with medications that block aldosterone can reduce that risk. This study is trying to learn whether treatment with a medication that blocks aldosterone can improve heart function in people who make too much aldosterone.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Primary Aldosteronism
• Hypertension

Eligibility basics and study details

Study type

Interventional

Phase

Phase 4

Ages

18 to 85 years

Sex

All

Healthy volunteers

Not accepted

Sponsor

Brigham and Women's Hospital

Last updated on ClinicalTrials.gov

October 15, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites