Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)
NCT05008276
This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .
Summary
Early diabetic kidney disease (DKD) occurs in 50-70% of youth with type 2 diabetes (T2D) and confers high lifetime risk of dialysis and premature death. Youth-onset T2D typically manifests during or shortly after puberty in adolescents with obesity. Epidemiological data implicate puberty as an accelerator of kidney disease in youth with obesity and diabetes and the investigators posit that the link between puberty and T2D-onset may explain the high burden of DKD in youth-onset T2D.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Type 2 Diabetes Mellitus
- Diabetic Kidney Disease
- Adolescent Obesity
- Pre Diabetes
- Kidney Hypoxia
- Puberty
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 8 to 14 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Petter Bjornstad
- Last updated on ClinicalTrials.gov
- March 24, 2025
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Colorado · 1
- Children's Hospital Colorado · Aurora, CO
Washington · 1
- Seattle Children's Hospital · Seattle, WA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.