Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies
NCT04888936
This study is recruiting at 2 US sites in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
Background: RASopathies are a group of conditions caused by a genetic change. People with a RASopathy may have developmental issues, cognitive disability, poor growth, and birth defects. They may also have an increased risk for developing cancer. Researchers want to learn more. Objective: To learn more about RASopathies, how genes and environmental factors contribute to cancer development in people with RASopathies, and the best way to find these cancers and other conditions early or prevent them. Eligibility: People of any age who have or may have a RASopathy, and their family members.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Costello Syndrome
- Noonan Syndrome
- Cardiofaciocutaneous Syndrome
- Legius Syndrome
- Capillary Arteriovenous Malformation Syndrome
- RASopathy
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 1 month to 99 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- National Cancer Institute (NCI)
- Last updated on ClinicalTrials.gov
- October 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Maryland · 2
- National Institutes of Health Clinical Center · Bethesda, MD
- National Cancer Institute - Shady Grove · Rockville, MD
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.