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Role of Microvascular Insulin Resistance and Cardiorespiratory Fitness Diabetes

NCT04791371

This study is recruiting at 2 US sites in 2 states, according to its ClinicalTrials.gov record last updated .

Summary

The goal of this two-site grant proposal is to determine the role of the decreased insulin-mediated muscle perfusion found in type 2 diabetes in contributing to the development of cardiac and skeletal muscle dysfunction and subsequent functional exercise impairment. In addition, it is also our goal to determine whether exercise training attenuates insulin resistance and restores insulin-mediated perfusion to the heart and to skeletal muscle, leading to improved cardiac function and exercise performance.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Type 2 Diabetes
  • Overweight and Obesity

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
30 to 55 years
Sex
All
Healthy volunteers
Accepted
Sponsor
University of Colorado, Denver
Last updated on ClinicalTrials.gov
March 23, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Colorado · 1

  • University of Colorado · Aurora, CO

Virginia · 1

  • University of Virginia · Charlottesville, VA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.