Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
NCT04712812
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or saliva) from male and female patients, under the age of 30, who exhibited early onset symptoms of HSP with (1) a clinical diagnosis of hereditary spastic paraplegia and (2) the presence of variants in HSP related genes and/or be a relative of a person with such a diagnosis.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Hereditary Spastic Paraplegia
- SPG47
- SPG50
- SPG51
- SPG52
- AP4-related Hereditary Spastic Paraplegia
- Early Onset Hereditary Spastic Paraplegia
- SPG4
- SPG3A
- SPG15
- SPG11
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- Up to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- Boston Children's Hospital
- Last updated on ClinicalTrials.gov
- March 18, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Massachusetts · 1
- Boston Children's Hospital · Boston, MA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.