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fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

NCT04439552

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Evaluation of neuroplasticity of pain pathways and corneal afferent nerve regeneration following corneal crosslinking (CXL) in keratoconus patients using fMRI and corneal In Vivo Confocal Microscopy (IVCM).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Pain, Postoperative
  • Pain, Chronic
  • Pain, Acute
  • Surgical Injury
  • Surgical Wound
  • Cornea Injury
  • Cornea
  • Keratoconus

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
8 to 35 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Boston Children's Hospital
Last updated on ClinicalTrials.gov
December 19, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Massachusetts · 1

  • Boston Children's Hospital · Boston, MA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.