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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

NCT04363684

This study is recruiting at 23 US sites in 19 states, according to its ClinicalTrials.gov record last updated .

Summary

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) represents the formalized integration of ARTFL (U54 NS092089; funded through 2019) and LEFFTDS (U01 AG045390; funded through 2019) as a single North American research consortium to study FTLD for 2019 and beyond.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Frontotemporal Lobar Degeneration (FTLD)
  • Progressive Supranuclear Palsy (PSP)
  • Corticobasal Degeneration (CBD)
  • Behavioral Variant Frontotemporal Dementia (bvFTD)
  • Semantic Variant Primary Progressive Aphasia (svPPA)
  • Nonfluent Variant Primary Progressive Aphasia (nfvPPA)
  • FTD With Amyotrophic Lateral Sclerosis (FTD/ALS)
  • Amyotrophic Lateral Sclerosis
  • Oligosymptomatic PSP (oPSP)
  • C9orf72
  • GRN Related Frontotemporal Dementia
  • MAPT Gene Mutation
  • TBK1 Gene Mutation
  • Oligosymptomatic Progressive Supranuclear Palsy

Eligibility basics and study details

Study type
Observational
Phase
Not applicable
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
Mayo Clinic
Last updated on ClinicalTrials.gov
October 7, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Alabama · 1

  • University of Alabama Birmingham · Birmingham, AL

California · 3

  • University of California, Los Angeles · Los Angeles, CA
  • University of California, San Diego · San Diego, CA
  • University of California San Francisco · San Francisco, CA

Colorado · 1

  • University of Colorado Denver · Denver, CO

Florida · 1

  • Mayo Clinic Florida · Jacksonville, FL

Georgia · 1

  • Emory University · Atlanta, GA

Illinois · 1

  • Northwestern University · Chicago, IL

Indiana · 1

  • Indiana University · Indianapolis, IN

Maryland · 2

  • Johns Hopkins University · Baltimore, MD
  • NIH · Bethesda, MD

Massachusetts · 1

  • Massachusetts General Hospital · Boston, MA

Michigan · 1

  • University of Michigan · Ann Arbor, MI

Minnesota · 1

  • Mayo Clinic Rochester · Rochester, MN

Missouri · 1

  • Washinton University in St. Louis · St Louis, MO

New York · 1

  • Columbia University · New York, NY

North Carolina · 1

  • University of North Carolina, Chapel Hill · Chapel Hill, NC

Ohio · 1

  • Case Western Reserve Medical Center · Cleveland, OH

Pennsylvania · 1

  • University of Pennsylvania · Philadelphia, PA

Tennessee · 1

  • Vanderbilt University · Nashville, TN

Texas · 2

  • Nantz National Alzheimer Center Houston · Houston, TX
  • UT San Antonio Health Science Center · San Antonio, TX

Washington · 1

  • University of Washington · Seattle, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.