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[18F]F-DOPA Imaging in Patients With Autonomic Failure

NCT04246437

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Alpha-synucleinopathies refer to age-related neurodegenerative and dementing disorders, characterized by the accumulation of alpha-synuclein in neurons and/or glia. The anatomical location of alpha-synuclein inclusions (Lewy Bodies) and the pattern of progressive neuronal death (e.g. caudal to rostral brainstem) give rise to distinct neurological phenotypes, including Parkinson's disease (PD), Multiple System Atrophy (MSA), Dementia with Lewy Bodies (DLB).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Autonomic Failure
  • Pure Autonomic Failure
  • Parkinson Disease
  • Multiple System Atrophy
  • Dementia With Lewy Bodies

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
Daniel Claassen
Last updated on ClinicalTrials.gov
March 16, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Tennessee · 1

  • Vanderbilt University Medical Center · Nashville, TN

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.