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Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

NCT04179981

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is highly prevalent in Veterans. Veterans with OVS may be at increased risk for cognitive deficits, poor sleep quality as well as a reduced quality of life (QoL). The overall objective is to study the effects of positive airway pressure therapy on clinical outcomes in patients with OVS.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Sleep Apnea Syndrome
  • Obstructive Sleep Apnea
  • COPD
  • Overlap Syndrome
  • Quality of Life
  • Neurocognitive Function
  • Sleepiness
  • Elderly
  • Positive Airway Pressure

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
60 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
VA Office of Research and Development
Last updated on ClinicalTrials.gov
June 5, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Michigan · 1

  • John D. Dingell VA Medical Center, Detroit, MI · Detroit, MI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.