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COPD Clinical Trials Recruiting in the US

99 studies for COPD are recruiting at 1,003 US sites, according to ClinicalTrials.gov data processed .

Chronic obstructive pulmonary disease (COPD) is a long-term lung condition that limits airflow and makes it harder to breathe.

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Recruiting now

Top COPD studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

    NCT06283966

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    135 US recruiting sites
  2. Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

    NCT07190222

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    74 US recruiting sites
  3. A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

    NCT07082738

    • Phase 2
    • Ages 40 years and older
    • Sex: All
    Recruiting sites
    72 US recruiting sites
  4. Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

    NCT07190209

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    71 US recruiting sites
  5. A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

    NCT06883305

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    59 US recruiting sites
  6. A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

    NCT06878261

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    57 US recruiting sites
  7. Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

    NCT06961214

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    57 US recruiting sites
  8. A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

    NCT07363694

    • Phase 2/3
    • Ages 35 to 80 years
    • Sex: All
    Recruiting sites
    52 US recruiting sites
  9. Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation

    NCT06959095

    • Phase 3
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    42 US recruiting sites
  10. eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

    NCT07177339

    • Phase 3
    • Ages 40 to 75 years
    • Sex: All
    Recruiting sites
    42 US recruiting sites
  11. Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

    NCT06122077

    • Observational
    • Ages 50 years and older
    • Sex: All
    Recruiting sites
    36 US recruiting sites
  12. myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

    NCT05204888

    • Interventional
    • Ages 30 years and older
    • Sex: All
    Recruiting sites
    25 US recruiting sites
  13. To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

    NCT07684820

    • Phase 2
    • Ages 40 to 85 years
    • Sex: All
    Recruiting sites
    22 US recruiting sites
  14. An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

    NCT06035120

    • Interventional
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    18 US recruiting sites
  15. Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

    NCT06891755

    • Interventional
    • Ages 40 to 84 years
    • Sex: All
    Recruiting sites
    18 US recruiting sites
  16. STRIVE Post-Market Registry Study

    NCT04302272

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    15 US recruiting sites
  17. SPIROMICS Study of Early COPD Progression (SOURCE)

    NCT05033990

    • Observational
    • Ages 30 to 55 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    14 US recruiting sites
  18. A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

    NCT07759245

    • Phase 2
    • Ages 40 to 75 years
    • Sex: All
    Recruiting sites
    14 US recruiting sites
  19. Multi-Center Clean Air Randomized Controlled Trial in COPD

    NCT06376994

    • Phase 3
    • Ages 40 years and older
    • Sex: All
    Recruiting sites
    11 US recruiting sites
  20. A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

    NCT07053423

    • Phase 4
    • Ages 40 to 85 years
    • Sex: All
    Recruiting sites
    11 US recruiting sites
  21. Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

    NCT07059091

    • Phase 2
    • Ages 40 years and older
    • Sex: All
    Recruiting sites
    10 US recruiting sites
  22. A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)

    NCT07646587

    • Phase 2
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    8 US recruiting sites
  23. The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry

    NCT07612878

    • Observational
    • Ages 40 years and older
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  24. A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis

    NCT07725939

    • Phase 2
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    7 US recruiting sites
  25. Collection of Blood From Healthy Patients, Patients With Benign Disease and Patients With Cancer

    NCT05181826

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    6 US recruiting sites
  26. Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

    NCT07051707

    • Interventional
    • Ages 40 to 80 years
    • Sex: All
    Recruiting sites
    6 US recruiting sites
  27. WIN Ratio Analysis to Determine a Strategy of Non- Invasive SUpport for Respiratory Failure in the EmeRgency Department

    NCT07558265

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    6 US recruiting sites
  28. Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

    NCT05937854

    • Phase 2
    • Ages 35 to 89 years
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  29. Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

    NCT06390345

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    5 US recruiting sites
  30. A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

    NCT06603246

    • Phase 1
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    5 US recruiting sites

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COPD clinical trials by city

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining a COPD clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.