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Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

NCT04118387

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

Central sleep apnea (CSA) is common in patients with heart failure and those using opioid analgesics. Unfortunately, effective treatment of central apnea remains elusive, pressure therapy given the modest efficiency of positive airway pressure therapy. The focus of this proposal is to identify mechanistic pathways to guide future therapeutic interventions for central sleep apnea based on the strong premise that multi-modality therapy will normalize respiration and hence mitigate adverse long-term consequences of CSA.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Sleep Disordered Breathing
  • Able Bodied

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
VA Office of Research and Development
Last updated on ClinicalTrials.gov
July 20, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Michigan · 1

  • John D. Dingell VA Medical Center, Detroit, MI · Detroit, MI

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.