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Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

NCT03887481

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

AD afflicts over 5.5. million Americans and is one of the most expensive diseases worldwide. In AD the variant in which language functions are most affected are referred to as 'logopenic variant Primary Progressive Aphasia' (lvPPA). Language deficits dramatically impair communication and quality of life for both patients and caregivers. PPA usually has an early onset (50-65 years of age), detrimentally affecting work and family life. Studies have identified verbal short-term memory/working memory (vSTM/WM) as a primary deficit and cause of language impairment.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Logopenic Progressive Aphasia
  • Primary Progressive Aphasia

Eligibility basics and study details

Study type
Interventional
Phase
Not applicable
Ages
50 to 80 years
Sex
All
Healthy volunteers
Accepted
Sponsor
Johns Hopkins University
Last updated on ClinicalTrials.gov
September 9, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 1

  • Johns Hopkins Hospital · Baltimore, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.