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Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

NCT03737292

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to assess pharmacokinetics of liposomal bupivacaine (Exparel) after multilevel intercostal injections of this local anesthetic for pain control during and after thoracoscopic surgeries. The specific aim of this study is to evaluate plasma concentration of bupivacaine after intraoperative intercostal injections of 266 mg of liposomal bupivacaine and compare it to plasma concentrations of bupivacaine after intercostal injections of 2mg/kg of 0.5% plain Bupivacaine with maximal dose of 30 ml or 150 mg.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Pain, Postoperative
  • Pharmacokinetics

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Milton S. Hershey Medical Center
Last updated on ClinicalTrials.gov
June 12, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Pennsylvania · 1

  • Milton S. Hershey Medical Center · Hershey, PA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.