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Identifying Correlates of Brain Microglial Activation in Neuropsychiatric Syndromes: a Dimensional Approach

NCT03705715

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this research is to determine whether there is more extensive inflammation in the brain of people with clinical evidence of neuropsychiatric syndromes, such as mood disorder, chronic pain syndrome, dementia, traumatic brain injury, or substance abuse. The research will also explore whether there is more inflammation in patients with more neuropsychiatric symptoms. Inflammation in the brain will identified by using Positron Emission Tomography (PET) with the radiotracer [11C]PBR-28 or [11C]ER176.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Neuropsychiatric Syndromes

Eligibility basics and study details

Study type
Interventional
Phase
Phase 1
Ages
18 to 80 years
Sex
All
Healthy volunteers
Accepted
Sponsor
The University of Texas Health Science Center, Houston
Last updated on ClinicalTrials.gov
March 19, 2025

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Texas · 1

  • BBSB at UTHealth · Houston, TX

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.