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CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

NCT03705585

This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

This is an open-label, non-randomized study. The purpose of this study is to better understand how vaccines against typhoid fever and cholera affect the normal immune system and bacteria in the intestine. Patients having standard-of-care endoscopies (colonoscopy and/or esophagogastroduodenoscopy (EGD)) will be divided into 3 groups: Group 1: Vivotif typhoid vaccination and/or Vaxchora cholera vaccination then endoscopy Group 2: Endoscopy, then Vivotif typhoid vaccination and/or Vaxchora cholera vaccination, then follow-up endoscopy Group 3: Endoscopy without vaccination.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Typhoid and/or Cholera Vaccination

Eligibility basics and study details

Study type
Interventional
Phase
Phase 4
Ages
18 years and older
Sex
All
Healthy volunteers
Accepted
Sponsor
University of Maryland, Baltimore
Last updated on ClinicalTrials.gov
September 4, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Maryland · 1

  • University of Maryland, Baltimore, Center for Vaccine Development and Global Health · Baltimore, MD

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.