Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic Failure
NCT02897063
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is to learn more about the effects of midodrine and droxidopa, two medications used for the treatment of orthostatic hypotension (low blood pressure on standing), on the veins of the abdomen of patients with autonomic failure. The study will be conducted at Vanderbilt University Medical Center, and consists of 2 parts: a screening and 2 testing days. The total length of the study will be about 5 days. About 34 participants will be screened for the study.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Autonomic Failure
- Pure Autonomic Failure
- Multiple System Atrophy
- Parkinson Disease
- Orthostatic Hypotension
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Phase 1
- Ages
- 40 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Sponsor
- Vanderbilt University Medical Center
- Last updated on ClinicalTrials.gov
- October 14, 2025
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Tennessee · 1
- Autonomic Dysfunction Center/ Vanderbilt University Medical Center · Nashville, TN
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.