The NIH MINI Study: Metabolism, Infection, and Immunity in Inborn Errors of Metabolism
NCT01780168
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
The Metabolism, Infection and Immunity (MINI) Study is a longitudinal natural history study at the National Institutes of Health (NIH) that aims to define the relationship between infection, immunity and clinical decline in individuals with mitochondrial disease. Mitochondrial diseases are a group of disorders caused by problems with the cell s ability to produce energy. Infection in individuals with mitochondrial disease can lead to worsening clinical symptoms, particularly neurologic symptoms.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Oxidative Phosphorylation Deficiencies
- Electron Transport Chain Disorders, Mitochondrial
- Mitochondrial Disorders
- Leigh Disease
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 4 weeks to 115 years
- Sex
- All
- Healthy volunteers
- Accepted
- Sponsor
- National Human Genome Research Institute (NHGRI)
- Last updated on ClinicalTrials.gov
- October 13, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Maryland · 1
- National Institutes of Health Clinical Center · Bethesda, MD
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.