Acute Progesterone Suppression of Wake vs. Sleep Luteinizing Hormone Pulse Frequency in Pubertal Girls With and Without Hyperandrogenism
NCT00929006
This study is recruiting at 1 US site in 1 state, according to its ClinicalTrials.gov record last updated .
Summary
The purpose of this study is two-fold. (1) We will determine if in mid- to late pubertal girls without hyperandrogenism (HA), progesterone (P4) acutely reduces waking luteinizing hormone (LH) frequency to a greater extent than sleep-associated LH frequency. (2) We will determine if in mid- to late pubertal girls with HA, P4 will acutely suppress waking LH frequency to a lesser degree than it does in girls without HA.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Puberty
- Hyperandrogenism
Eligibility basics and study details
- Study type
- Interventional
- Phase
- Early Phase 1
- Ages
- 10 to 17 years
- Sex
- Female
- Healthy volunteers
- Accepted
- Sponsor
- University of Virginia
- Last updated on ClinicalTrials.gov
- August 5, 2025
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Virginia · 1
- University of Virginia · Charlottesville, VA
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.