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Irritable Bowel Syndrome (IBS) Clinical Trials Recruiting in the US

31 studies for Irritable Bowel Syndrome (IBS) are recruiting at 174 US sites, according to ClinicalTrials.gov data processed .

Irritable bowel syndrome (IBS) is a common digestive condition that can cause stomach pain, bloating and changes in bowel habits.

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Recruiting now

Top Irritable Bowel Syndrome (IBS) studies by number of US sites

Showing 30 studies, most US recruiting sites first.
  1. A Study to Investigate Abdominal Symptoms With Camlipixant Compared With Placebo in Adults With Irritable Bowel Syndrome - Diarrhea (IBS-D) and Irritable Bowel Syndrome - Mixed (IBS-M)

    NCT07519395

    • Phase 2
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    114 US recruiting sites
  2. A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Diarrhea (IBS-D)

    NCT07545759

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    14 US recruiting sites
  3. A Study of Brenipatide (LY3537031) in Participants With Irritable Bowel Syndrome-Constipation (IBS-C)

    NCT07545772

    • Phase 2
    • Ages 18 to 75 years
    • Sex: All
    Recruiting sites
    14 US recruiting sites
  4. A Prospective Trial of a Variable Compression System for Moderate to Severe Irritable Bowel Syndrome

    NCT07540312

    • Interventional
    • Ages 18 to 60 years
    • Sex: All
    Recruiting sites
    3 US recruiting sites
  5. IBS Skin Patch Test Food Allergy Study

    NCT06288672

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  6. Feasibility Study of a Guided Imagery Therapy Mobile Application for Functional Abdominal Pain Disorders in Children

    NCT07222943

    • Interventional
    • Ages 7 to 12 years
    • Sex: All
    Recruiting sites
    2 US recruiting sites
  7. Mucosal and Microbiota Changes During Acute Campylobacteriosis

    NCT03223077

    • Observational
    • Ages 18 to 80 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  8. Low FODMAP Plus PEG 3350 for the Treatment of Patients with Irritable Bowel Syndrome-Constipation

    NCT03687814

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  9. Indiana University Gastrointestinal Motility Diagnosis Registry

    NCT04506593

    • Observational
    • Ages Any age
    • Sex: All
    Recruiting sites
    1 US recruiting site
  10. Home Transcutaneous Electrical Acustimulation (TEA)

    NCT05519683

    • Phase 2/3
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  11. Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome

    NCT05719246

    • Interventional
    • Ages 12 to 21 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  12. Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children

    NCT05730491

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  13. Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

    NCT05754190

    • Observational
    • Ages 18 years and older
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  14. Fecal Microbiota Transplantation for IBS

    NCT05776914

    • Phase 2
    • Ages 18 to 70 years
    • Sex: Female
    Recruiting sites
    1 US recruiting site
  15. A Study of Virtual Reality and Linaclotide for IBS-C

    NCT05796388

    • Interventional
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  16. Mechanisms of Gulf War Illness

    NCT05972291

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  17. The Use of Directed Probiotics in ME/CFS: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

    NCT06211062

    • Phase 2
    • Ages 45 to 70 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  18. Capsule Microbiota Sampling in IBS/Functional Gastrointestinal Disease

    NCT06215222

    • Observational
    • Ages 18 to 70 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  19. Visible Abdominal Distension

    NCT06369753

    • Interventional
    • Ages 18 to 80 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  20. Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain

    NCT06381921

    • Interventional
    • Ages 18 to 50 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  21. Psyllium in Pediatric IBS

    NCT06639984

    • Phase 2
    • Ages 12 to 17 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  22. Irritable Bowel Syndrome and Control Volunteers: Diet Challenge

    NCT06668922

    • Interventional
    • Ages 18 to 75 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  23. Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator

    NCT06684470

    • Early Phase 1
    • Ages 18 to 70 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  24. Prospective Observational Study of Naturopathic Approaches to IBS

    NCT06721624

    • Observational
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  25. Efficacy of Rifaximin With NAC in IBS-D

    NCT06727422

    • Phase 2
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  26. Home-based Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for IBS Pain

    NCT06847360

    • Interventional
    • Ages 18 to 29 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  27. Well-being in IBS: Strengths and Happiness (WISH) 2.0

    NCT06866106

    • Interventional
    • Ages 18 years and older
    • Sex: All
    Recruiting sites
    1 US recruiting site
  28. Diet and Motility in IBS

    NCT07283341

    • Observational
    • Ages 8 to 18 years
    • Sex: All
    • Accepts healthy volunteers
    Recruiting sites
    1 US recruiting site
  29. Drug Interaction Potential of Pro-Inflammatory Conditions

    NCT07360938

    • Observational
    • Ages 12 to 99 years
    • Sex: All
    Recruiting sites
    1 US recruiting site
  30. Defining Objective Markers of Compliance for Dietary Therapies in IBS

    NCT07494968

    • Interventional
    • Ages 18 to 65 years
    • Sex: All
    Recruiting sites
    1 US recruiting site

FAQ

Common questions

What is a clinical trial?
A clinical trial is a research study in people that tests a medical, surgical or behavioral intervention, such as an investigational drug or device. Observational studies are also listed: they collect information without assigning a treatment. Read how clinical trials work.
Is there compensation for joining an Irritable Bowel Syndrome (IBS) clinical trial?
Compensation for time and travel may be available, but it varies by study and some studies offer none. The amount and schedule are reviewed by an ethics board and described in the consent form. See compensation in clinical trials.
How do I check if I'm eligible?
Each study lists age, sex and other inclusion and exclusion criteria on its ClinicalTrials.gov record. Only the study team can confirm eligibility, usually through a screening call or visit. Talk with your own doctor before joining any study.

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.