The Immunobiological Mechanisms of Depression in Perimenopause
NCT07910552
This study is recruiting at 3 US sites in 2 states, according to its ClinicalTrials.gov record last updated .
Summary
This project aims to identify immunobiological mechanisms underlying the development of depression during the perimenopause. During the perimenopause, the risk for recurrence of depression is increased 13-fold among women who previously had depression. Moreover, perimenopause overlaps with the age span exhibiting the highest suicide rate for women. The perimenopause can last for several years and starts when estrogen and progesterone levels begin to fluctuate, gradually declining.
Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov
Conditions studied
- Perimenopause
- Major Depressive Episode (MDE)
Eligibility basics and study details
- Study type
- Observational
- Phase
- Not applicable
- Ages
- 40 to 55 years
- Sex
- Female
- Healthy volunteers
- Accepted
- Sponsor
- Van Andel Research Institute
- Last updated on ClinicalTrials.gov
- November 2, 2026
These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.
US recruiting sites
Michigan · 2
- Pine Rest Christian Mental Health · Grand Rapids, MI
- Western Michigan University Homer Stryker M.D. School of Medicine · Kalamazoo, MI
New York · 1
- Weill Cornell Medicine · New York, NY
Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.