Biofluid Research on Age-Related or Inherited Neurodegeneration

Summary

The aim of this study is to contribute to and continue to sustain a repository of blood samples, nucleic acid (DNA and/or RNA) samples, family history information, and other demographic information from individuals with age-related neurodegenerative conditions, or their family members who may or may not be at risk for similar conditions. This study will continue to further expand research into the molecular and genetic basis of these diseases and their risk factors.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

• Frontotemporal Degeneration (FTD)
• ALS (Amyotrophic Lateral Sclerosis)
• Primary Progressive Aphasia (PPA)
• Familial Frontotemporal Lobar Degeneration (fFTLD)
• Fronto-temporal Lobar Dementia
• Dementia With Lewy Bodies (DLB)
• Cortical Basal Syndrome (CBS)
• Alzheimer's Disease (AD)
• Progressive Supranuclear Palsy(PSP)
• Parkinson's Disease (PD)
• Parkinson's Disease Dementia (PDD)
• Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)
• Posterior Cortical Atrophy (PCA)
• Primary Lateral Sclerosis (PLS)
• Primary Muscular Atrophy (PMA)

Eligibility basics and study details

Study type

Observational

Phase

Not applicable

Ages

18 years and older

Sex

All

Healthy volunteers

Accepted

Sponsor

University of Pennsylvania

Last updated on ClinicalTrials.gov

September 1, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites