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Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease

NCT07750158

This study is recruiting at 13 US sites in 3 states, according to its ClinicalTrials.gov record last updated .

Summary

The primary objective of this study is to evaluate the effectiveness of zanzalintinib + Pembrolizumab (+) berahyaluronidase alfa and zanzalintinib alone compared with placebo.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Colorectal Cancer

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Exelixis
Last updated on ClinicalTrials.gov
September 21, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

Iowa · 1

  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Council Bluffs · Council Bluffs, IA

Nebraska · 6

  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Grand Island · Grand Island, NE
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Regional · Grand Island, NE
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Bergan · Omaha, NE
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Legacy · Omaha, NE
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Methodist · Omaha, NE
  • Oncology Hematology West, PC dba Nebraska Cancer Specialists - Papillion · Papillion, NE

New Jersey · 6

  • Astera Cancer Care · Bridgewater, NJ
  • Astera Cancer Care · East Brunswick, NJ
  • Astera Cancer Care · Edison, NJ
  • Astera Cancer Care · Monroe, NJ
  • Astera Cancer Care · Somerset, NJ
  • Astera Cancer Care · Toms River, NJ

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.