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Exercise and Intranasal Insulin in Type 2 Diabetes

NCT07675499

This study is recruiting at 4 US sites in 1 state, according to its ClinicalTrials.gov record last updated .

Summary

About 6.5 million adults in the United States who are 65 or older have dementia. While the exact cause of dementia is not known, it may be due to changes in the brain. Further, risk may be higher when the brain does not respond to insulin. Indeed, brain insulin resistance has emerged as a pathologic factor affecting memory, executive function as well as systemic glucose control. Regular aerobic exercise may help reduce the risk of dementia by increased blood flow to the brain and help the brain respond better to insulin.

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Type 2 Diabetes
  • Insulin Sensitivity/Resistance
  • Cognition
  • Brain Blood Flow

Eligibility basics and study details

Study type
Interventional
Phase
Phase 2/3
Ages
55 to 80 years
Sex
All
Healthy volunteers
Not accepted
Sponsor
Rutgers, The State University of New Jersey
Last updated on ClinicalTrials.gov
June 30, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

New Jersey · 4

  • Institute for Food, Nutrition, and Health · New Brunswick, NJ
  • Robert Wood Johnson University Hospital Clinical Research Center · New Brunswick, NJ
  • Rutgers University Loree Gymnasium · New Brunswick, NJ
  • Center for Advanced Human Brain Imaging Research · Piscataway, NJ

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.