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A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration

NCT07614776

This study is recruiting at 55 US sites in 23 states, according to its ClinicalTrials.gov record last updated .

Summary

The aim of this trial is to demonstrate similarity in efficacy between ABP 938 8 mg and aflibercept (US) 8 mg by evaluating the change in best corrected visual acuity (BCVA) in participants with neovascular age-related macular degeneration (nAMD)

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Neovascular Age-related Macular Degeneration
  • nAMD

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
50 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Amgen
Last updated on ClinicalTrials.gov
October 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 6

  • Retina Consultants of Orange County · Fullerton, CA
  • South Coast Retina Center - RCA · Long Beach, CA
  • Retinal Consultants Medical Group, Inc - Modesto (RCA) · Modesto, CA
  • California Eye Specialists Medical Group, Inc · Pasadena, CA
  • Retinal Consultants Medical Group, Inc - Sacramento - Parkcenter Drive (RCA) · Sacramento, CA
  • California Retina Consultants · Santa Barbara, CA

Colorado · 3

  • Retina Consultants of Southern Colorado (Colorado Springs)- RCA · Colorado Springs, CO
  • Retina Consultants of Southern Colorado (Pueblo)- RCA · Colorado Springs, CO
  • Colorado Retina Associates (RCA) · Lakewood, CO

Connecticut · 1

  • Retina Group of New England · Waterford, CT

Florida · 3

  • Medeye Associates - Research · Miami, FL
  • Retina Consultants of Southwest Florida - Naples · Naples, FL
  • Advanced Research, LLC · Pensacola, FL

Illinois · 2

  • University Retina - Bedford Park Location · Chicago, IL
  • Retina Associates · Elmhurst, IL

Indiana · 1

  • Associated Vitreoretinal and Uveitis Consultants · Carmel, IN

Maryland · 3

  • The Retina Care Center- Baltimore (PRISM Vision Group) · Baltimore, MD
  • Mid Atlantic Retina Specialists · Hagerstown, MD
  • Retina Specialists · Towson, MD

Massachusetts · 1

  • Ophthalmic Consultants of Boston · Boston, MA

Minnesota · 1

  • Retina Consultants of Minnesota (RCM) - St. Louis Park · Edina, MN

Mississippi · 1

  • Mississippi Retina Assoc · Madison, MS

Missouri · 1

  • The Retina Institute, Research Retina Institute (RCA) · St Louis, MO

New Jersey · 1

  • Envision Ocular, LLC · Bloomfield, NJ

New Mexico · 1

  • Vision Research Center Eye Associates of New Mexico · Albuquerque, NM

New York · 3

  • Retina Vitreous Surgeons of CNY, PC · Liverpool, NY
  • Ophthalmic Consultants of Long Island - Research · Oceanside, NY
  • Long Island Vitreoretinal Consultants(RCA Network) · Scarsdale, NY

North Carolina · 2

  • North Carolina Retina Associates · Raleigh, NC
  • NC Retina Associates- RCA · Wake Forest, NC

Ohio · 1

  • Midwest Retina - Main Office · Dublin, OH

Pennsylvania · 1

  • Eye Care Specialists - Kingston · Kingston, PA

South Carolina · 6

  • Retina Consultants of South Carolina, Charleston Neuroscience institute - Blufffon (RCA) · Beaufort, SC
  • Charleston Neuroscience Institute · Charleston, SC
  • Palmetto Retina Center - Main (RCA) · Columbia, SC
  • Retina Consultants of South Carolina, Charleston Neuroscience Institute- Ladson (RCA) · Ladson, SC
  • Retina Consultants of South Carolina, Charleston Neuroscience Institute- Mount Pleasant (RCA) · Mt. Pleasant, SC
  • Palmetto Retina Center, Florence (RCA) · West Columbia, SC

Tennessee · 1

  • Tennessee Retina PC · Nashville, TN

Texas · 11

  • Texas Retina Associates (TRA) - Arlington · Arlington, TX
  • Austin Retina Associates · Austin, TX
  • Austin Retina Associates - Ophthalmology/Retina · Austin, TX
  • Retina Consultants of Texas - Bellaire · Bellaire, TX
  • Texas Retina Associates (TRA) - Dallas Main · Dallas, TX
  • Texas Retina Associates - Fort Worth · Fort Worth, TX
  • Retina Consultants of Texas - Katy Retina Center · Houston, TX
  • Retina Consultants of Texas - The Woodlands · Katy, TX
  • Retinal Consultants of Texas- San Antonio · San Antonio, TX
  • Retina Consultants of Texas - Schertz · Schertz, TX
  • Strategic Clinical Research Group, LLC · Willow Park, TX

Utah · 1

  • Retina Associates of Utah - Retina Specialist · Salt Lake City, UT

Virginia · 1

  • Emerson Clinical Research- Virginia Retina Specialists · Falls Church, VA

Washington · 3

  • Vitreoretinal Associates of Washington · Bellevue, WA
  • Retina Center NW PLLC · Silverdale, WA
  • Spokane Eye Clinic (OCT and optical exam · Spokane, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.