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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

NCT07577843

This study is recruiting at 22 US sites in 16 states, according to its ClinicalTrials.gov record last updated .

Summary

The purpose of this study is to assess how well JNJ-78934804 works (efficacy) and how safe it is (safety) as compared to guselkumab at Week 48 in participants with moderately to severely active Crohn's disease (a long-term, progressive [worsens with time] and life-threatening disease of the intestine).

Shortened from the sponsor's brief summary. View official record on ClinicalTrials.gov

Conditions studied

  • Crohn Disease

Eligibility basics and study details

Study type
Interventional
Phase
Phase 3
Ages
18 years and older
Sex
All
Healthy volunteers
Not accepted
Sponsor
Janssen Research & Development, LLC
Last updated on ClinicalTrials.gov
October 14, 2026

These are the basic criteria only. The full inclusion and exclusion criteria are on the official record, and the study team decides who can take part.

US recruiting sites

California · 4

  • Clinnova Research · Anaheim, CA
  • Gastro SB Clinic · Chula Vista, CA
  • United Medical Doctors · Los Alamitos, CA
  • Medical Associates Research Group, Inc. · San Diego, CA

Colorado · 1

  • Peak Gastroenterology Associates · Colorado Springs, CO

Florida · 3

  • Florida Research Center Inc. · Lakewood Rch, FL
  • Sanchez Clinical Research, Inc · Miami, FL
  • GCP Clinical Research · Tampa, FL

Georgia · 1

  • Atlanta Gastroenterology Specialists · Suwanee, GA

Kentucky · 1

  • Tri-State Gastroenterology Assoc · Crestview Hills, KY

Louisiana · 2

  • Gastroenterology Clinic of Acadiana · Lafayette, LA
  • GIA Metairie · Metairie, LA

Michigan · 1

  • Michigan Center of Medical Research · Farmington Hills, MI

Missouri · 1

  • GIA Kansas City · Lee's Summit, MO

New York · 1

  • New York Gastroenterology Associates · New York, NY

North Carolina · 1

  • University of North Carolina Hospital · Chapel Hill, NC

Ohio · 1

  • Great Lakes Gastroenterology Research, LLC · Mentor, OH

Oklahoma · 1

  • Digestive Disease Specialists Inc · Oklahoma City, OK

Oregon · 1

  • The Oregon Clinic · Portland, OR

Tennessee · 1

  • Gastro One · Cordova, TN

Texas · 1

  • Tyler Research Institute, LLC · Tyler, TX

Washington · 1

  • GI Alliance Tacoma · Tacoma, WA

Source: ClinicalTrials.gov, data processed . Recruiting US sites filtered by distance and site status; summaries shortened.